Yes! Growing squash up a trellis or even a ladder is a fun way to save space in the garden and makes growing squash even in the front yard attractive. The trick is to provide slings for the squash as it forms if you plant a heavy variety. Nylon stockings work well as slings that can be placed under squash once they are bigger than a grapefruit and the ends of the stockings can be tided to the trellis to support the harvest. Keep growing, Marianne Binetti